Fig 1: Fold change of biomarker expression ACTN1, BAX, DDB2, FDXR, TSPYL2 and p53 at days 2, 4 and 8 across low (0–1 Gy), medium (2–5 Gy) and high (6–10 Gy) dose ranges. Fold changes were computed by calculating the ratio of the post-exposure biomarker MFI to the mean pre-irradiation baseline MFI of control NHPs. The bars represent the mean, the error bars represent the standard error of mean (SEM), p value represent significance between dose groups by Welch’s ANOVA test.